À propos du site :

Nom de domaine - btmf.fr

Titre du site - Bravo ! Votre domaine btmf.fr a bien été créé avec LWS !

Aller sur un site Internet - Bravo ! Votre domaine btmf.fr a bien été créé avec LWS !

Localisation GEO du site

Localisation Pays - France

Fournisseur - Groupe LWS SARL

Site Logo

adresse IP:

185.135.132.103

Serveurs de noms de domaine:

ns3.lwsdns.com ns2.lws-hosting.org ns4.lwsdns.com ns1.lws-hosting.org

Tous les enregistrements:

☆ btmf.fr. 3600 IN TXT "v=spf1 mx:btmf.fr a:mail.btmf.fr a:mailphp.lws-hosting.com -all"
☆ btmf.fr. 3600 IN AAAA 2a00:7ee0:1:0:3:37:0:362
☆ btmf.fr. 3600 IN SOA ns1.lws-hosting.org. hostmaster.btmf.fr. 1694502515 25200 3600 604800 3600
☆ btmf.fr. 3600 IN NS ns2.lws-hosting.org.
☆ btmf.fr. 3600 IN NS ns4.lwsdns.com.
☆ btmf.fr. 3600 IN NS ns1.lws-hosting.org.
☆ btmf.fr. 3600 IN NS ns3.lwsdns.com.
☆ btmf.fr. 3600 IN MX 10 mail.btmf.fr.
☆ btmf.fr. 21600 IN A 185.135.132.103

%% This is the AFNIC Whois server.
%%
%% complete date format: YYYY-MM-DDThh:mm:ssZ
%%
%% Rights restricted by copyright.
%% See https://www.afnic.fr/en/domain-names-and-support/everything-there-is-to-know-about-domain-names/find-a-domain-name-or-a-holder-using-whois/
%%
%%

domain: btmf.fr
status: ACTIVE
eppstatus: active
hold: NO
holder-c: ANO00-FRNIC
admin-c: O15320-FRNIC
tech-c: SL6122-FRNIC
registrar: SAS Ligne Web Services - LWS
Expiry Date: 2025-01-10T10:47:00Z
created: 2017-01-10T10:47:00Z
last-update: 2024-02-29T23:11:53.104713Z
source: FRNIC

nserver: ns1.lws-hosting.org
nserver: ns2.lws-hosting.org
nserver: ns3.lwsdns.com
nserver: ns4.lwsdns.com
source: FRNIC

registrar: SAS Ligne Web Services - LWS
address: 2 Rue Jules Ferry
address: 88190 GOLBEY
country: FR
phone: +33.177623003
fax-no: +33.329384707
e-mail: afnic@lws.fr
website: https://www.lws.fr/
anonymous: No
registered: 2007-01-01T00:00:00Z
source: FRNIC

nic-hdl: SL6122-FRNIC
type: ORGANIZATION
contact: SARL LWS
address: SARL LWS
address: 10, rue Penthievre
address: 75008 Paris
country: FR
phone: +33.826102413
e-mail: domaine@lws.fr
registrar: SAS Ligne Web Services - LWS
changed: 2024-07-03T08:11:45.86636Z
anonymous: NO
obsoleted: NO
eppstatus: associated
eppstatus: active
eligstatus: ok
eligsource: REGISTRAR
eligdate: 2021-02-23T00:00:00Z
reachstatus: ok
reachmedia: email
reachsource: REGISTRAR
reachdate: 2021-02-23T00:00:00Z
source: FRNIC

nic-hdl: O15320-FRNIC
type: ORGANIZATION
contact: ORDILAN
address: ORDILAN
address: 87, avenue de palavas
address: 34070 Montpelier
country: FR
phone: +33.611292282
e-mail: saidms@free.fr
registrar: SAS Ligne Web Services - LWS
anonymous: NO
obsoleted: NO
eppstatus: associated
eppstatus: active
eligstatus: not identified
reachstatus: not identified
source: FRNIC

nic-hdl: ANO00-FRNIC
type: PERSON
contact: Ano Nymous
registrar: SAS Ligne Web Services - LWS
changed: 2017-09-04T02:00:09Z
anonymous: YES
remarks: -------------- WARNING --------------
remarks: While the registrar knows him/her,
remarks: this person chose to restrict access
remarks: to his/her personal data. So PLEASE,
remarks: don't send emails to Ano Nymous. This
remarks: address is bogus and there is no hope
remarks: of a reply.
remarks: -------------- WARNING --------------
obsoleted: NO
eppstatus: associated
eppstatus: active
eligstatus: not identified
reachstatus: not identified
source: FRNIC

>>> Last update of WHOIS database: 2024-07-03T08:54:15.564336Z <<<

Brief facts about btmf:

Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic. Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored. The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring.

Antibiotic - An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections.

Streptomyces - Streptomyces is the largest genus of Actinomycetota, and the type genus of the family Streptomycetaceae. Over 700 species of Streptomyces bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, and have very large genomes with high GC content.

Secondary metabolite - Secondary metabolites, also called specialised metabolites, toxins, secondary products, or natural products, are organic compounds produced by any lifeform, e.g. bacteria, fungi, animals, or plants, which are not directly involved in the normal growth, development, or reproduction of the organism.

Peptide - Peptides are short chains of amino acids linked by peptide bonds. A polypeptide is a longer, continuous, unbranched peptide chain. Polypeptides which have a molecular mass of 10,000 Da or more are called proteins.

MRSA - Methicillin-resistant Staphylococcus aureus is a group of gram-positive bacteria that are genetically distinct from other strains of Staphylococcus aureus. MRSA is responsible for several difficult-to-treat infections in humans.

Vancomycin-resistant Enterococcus - Vancomycin-resistant Enterococcus, or vancomycin-resistant enterococci, are bacterial strains of the genus Enterococcus that are resistant to the antibiotic vancomycin.

Total synthesis

Peptides

Antibiotics